Strain Data Sheet

RBRC12366

Strain Information

Image
BRC No.RBRC12366
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Bglap/Bglap2<tm1Tok>
Former Common nameC57BL/6N Osteocalcin KO
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.
Takeshi Moriishi, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Tomoka Hasegawa, Toshihiro Miyazaki, Wenguang Liu, Ryo Fukuyama, Yuying Wang, Hisato Komori, Xin Qin, Norio Amizuka, Toshihisa Komori
PLoS Genet., 16(5) e1008586 (2020). 32463816

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Bglap
MGI:88156		bone gamma carboxyglutamate protein3Bglap<tm1Tok>
Bglap2
MGI:88157		bone gamma-carboxyglutamate protein 23Bglap2
neo neomycin resistance gene (E. coli)3 mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
Detailed phenotype data

Ordering Information

Donor DNAマウス PGK プロモーター, 大腸菌 neo 遺伝子, T7 ファージ gb2 (prokaryotic promoter)
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS Genet., 16(5) e1008586 (2020).
DepositorToshihisa KOMORI (Nagasaki University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data