Strain Data Sheet

RBRC11693

Strain Information

Image
BRC No.RBRC11693
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.B6129-Sf3b2<tm1Hko>
Former Common nameSf3b2
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain developmentDeposited by Haruhiko Koseki, RIKEN IMS in 2022. This strain was generated using R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> and mice were backcrossed to C57BL/6J for 11 times. C57BL/6J congenic line.
Strain descriptionSf3b2 KO mice. Homozygous mutants are embryonically lethal. A neo fragment was inserted at the intron immediately downstream of an exon of translation initiation codon.
Colony maintenance
ReferencesGenes Dev., 19(5):536-41 (2005). 15741318

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Sf3b2splicing factor 3b, subunit 219Sf3b2<tm1Hko>targeted mutation 1, Haruhiko Koseki

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)19

Ordering Information

Donor DNAE.col Neomycin resistant gene, Enterobacteria phage P1 loxp
Research applicationCre/loxP system
Specific Term and ConditionsThe RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorHaruhiko Koseki (RIKEN IMS)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data