Strain Information | |
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Image | |
BRC No. | RBRC11619 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Txn1<tm1Ksak> |
Former Common name | Thioredoxin(Trx) flox (Neo) mouse |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | Deposited by Kenji Sakimura, Niigata University in 2022. Mice were generated using RENKA ES cells derived from C57BL/6N. C57BL/6N genetic background. |
Strain description | Txn1 flox(Neo) mice. Frt-flanked Neo cassette with a loxP at 5’ is inserted at intron 1. Another loxP is inserted at intron 2. |
Colony maintenance | |
References | J. Biol. Chem., 283, 792-801 (2008). 18006499 Biochem. Biophys. Res. Commun., 369(2):281-6.(2008). 18307977 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site4Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP4loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | P1ファージ(クラス1) 病原性なし P1 ファージ部位特異的組換え認識配列 loxP (M10287), 大腸菌 病原性なし ネオマイシン耐性遺伝子, マウス 病原性なし pgk プロモーター, マウス 病原性なし pgk-PolyA, 酵母 病原性なし FRT配列 |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Biol Chem. 2008 Jan 11;283(2):792-801. Biochem Biophys Res Commun. 2008 May 2;369(2):281-6.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Kenji Sakimura (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |