Strain Data Sheet
RBRC11529
Strain Information | |
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| Image | |
| BRC No. | RBRC11529 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6J-Tg(Postn-NPPC)1Ncvcb |
| Former Common name | periostin-CNP Tg (C-type natriurtic peptide (CNP) transgenic mice in which CNP was placed under periostin promoter) |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Jun Hino, National Cerebral and Cardiovascular Center Hospital in 2021. C57BL/6J genetic background. |
| Strain description | Transgenic mice expressing human NPCC under the control of mouse Postn promoter. |
| Colony maintenance | |
| References | C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice. Kimura T, Nojiri T, Hino J, Hosoda H, Miura K, Shintani Y, Inoue M, Zenitani M, Takabatake H, Miyazato M, Okumura M, Kangawa K Respir. Res., 17:19 (2016). 26895702 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| NPPC | natriuretic peptide C (human) | UN | NPPC | mouse Periostin promoter | |||
| SV40 polyA | UN | ||||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | ヒト natriuretic peptide C (ゲノム、hCNP gene), マウス Periostin promoterを含むBac clone (RP23-144B14), サル SV40 poly A（ゲノムDNA） |
| Research application | Hematological Research Metabolism Research Mouse Models for Human Disease |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Respir. Res., 17:19 (2016).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the Co-Developer (Ensyo Takuya) using the Approval Form. |
| Depositor | Mikiya Miyazato (National Cerebral and Cardiovascular Center) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |