Strain Data Sheet
RBRC11528
Strain Information | |
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| Image | |
| BRC No. | RBRC11528 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6J-Tg(Tek-NPPC)1Ncvcb |
| Former Common name | E-CNP Tg (C-type natriurtic peptide (CNP) transgenic mice in which CNP was placed under Tie2 promoter and was overexpressed in endothelial cells) |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Jun Hino, National Cerebral and Cardiovascular Center Hospital in 2021. C57BL/6J genetic background. |
| Strain description | Transgenic mice expressing human NPCC under the control of mouse Tek promoter. |
| Colony maintenance | |
| References | Sci. Rep., 7(1):9807 (2017). 28852070 Life Sci., 209:349-356 (2018). 30114411 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter NPPCnatriuretic peptide C (human)UNNPPCmouse Tie2 promoter enhancer Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyAUN |
Ordering Information | |
|---|---|
| Donor DNA | ヒト natriuretic peptide C, マウス Tie2 promoter enhancer (ゲノムDNA), サル SV40 poly A（ゲノムDNA） |
| Research application | Hematological Research Immunology and Inflammation Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 7(1):9807 (2017).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the Co-Developer (Ensyo Takuya) using the Approval Form. |
| Depositor | Mikiya Miyazato (National Cerebral and Cardiovascular Center) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |