Strain Data Sheet
RBRC11498
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11498 |
| Type | CRISPR/Cas9 (Transgene) |
| Species | Mus musculus |
| Strain name | B6D2-Pabpn1l<em2(Pabpn1l/PA/1D4)Osb> |
| Former Common name | Pabpn1l<PA-1D4/PA-1D4> |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Masahito Ikawa, Research Institute for Microbial Diseases, Osaka University in 2021. Fertilized eggs derived from BDF1 × BDF1 were used to generate this line. Mixed genetic background. |
| Strain description | Knockin mice with PA and 1D4-tag at C-terminus of the Pabpn1l gene. |
| Colony maintenance | |
| References | PABPN1L is required for maternal mRNA degradation after meiosis resumption. Chihiro Emori, Mayo Kodani, Ferheen Abbasi, Masashi Mori, Masahito Ikawa J. Reprod. Dev., (2023). 38057116 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| 1D4 | 1D4 tag (synthetic) | 8 | 1D4 | ||||
| PA | PA tag (GVAMPGAEDDVV) (synthetic) human Podoplanin | 8 | PA | ||||
| Pabpn1l MGI:2685954 | poly(A)binding protein nuclear 1-like | 8 | Pabpn1l<em2Osb> | endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University | |||
| Pabpn1l | poly(A)binding protein nuclear 1-like | 8 | Pabpn1l | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Streptococcus pyogenes crRNA, tracrRNA, Mouse a part of Pabpn1l gene, synthetic PA tag, synthetic 1D4 tag |
| Research application | |
| Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
| Depositor | Masahito Ikawa (Osaka University) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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| No Data |