Strain Information | |
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Image | |
BRC No. | RBRC11486 |
Type | CRISPR/Cas9 (Transgene) |
Species | Mus musculus |
Strain name | B6D2-Gm1673<em1Osb> Tg(CAG-Gm1673/PA/1D4)1Osb |
Former Common name | Gm1673<-1862/wt>, CAG-Gm1673-PA/1D4 Tg #1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Masahito Ikawa, Research Institute for Microbial Diseases, Osaka University in 2021. Mixed genetic background of C57BL/6 x DBA/2. |
Strain description | Gm1673 KO mouse generated by the CRISPR/Cas9. 1862 bp deletion in the Gm1673 gene. This strain also has atransgene expressing Gm1673 fused with PA-1D4-tag (C-terminus) under the control of CAG promoter. |
Colony maintenance | |
References | Nat. Commun., 14(1):2354 (2023). doi: 10.1038/s41467-023-37984-x. 37095084 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gm1673predicted gene, 16735Gm1673<em1Osb>endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter 1D41D4 tag (synthetic)UN1D4 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gm1673predicted gene 1673UNGm1673CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter PAPA tag (GVAMPGAEDDVV) (synthetic) human PodoplaninUNPA |
Ordering Information | |
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Donor DNA | Streptococcus pyogenes crRNA, tracrRNA, Mouse a part of Gm1673 gene, chicken beta-actin promoter, CMV CMV IE enhancer, mouse Gm1673 cDNA, synthetic PA tag and 1D4 tag, rabbit globin polyA signal |
Research application | |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Commun., 14(1):2354 (2023). doi: 10.1038/s41467-023-37984-x.RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
Depositor | Masahito Ikawa (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |