Strain Information | |
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Image | |
BRC No. | RBRC11397 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C.129P2(B6)-Il5ra<tm1Ktk> |
Former Common name | BALB/c IL-5R alpha -/- |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Kiyoshi Takatsu, Institute of Medical Science in 1996. E14.1 ES cells were used. The mutant mice were backcrossed to BALB/c. |
Strain description | IL-5Ralpha gene knockout mice. A translational stop codon was introduced into exon 5 of the Il5ra and the exon 6 was replaced with a neo cassette. |
Colony maintenance | |
References | Immunity, 4(5):483-94 (1996). 8630733 Immunology, 102(3):289-300 (2001). 11298827 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Mouse IL-5R alpha genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity 4, 483-494 (1996)In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The depositor should be a co-author in the articles when the users publish their data using these mice for 1 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice. |
Depositor | Kiyoshi Takatsu (Toyama Prefectural Institute for Pharmaceutical Research) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |