Strain Information | |
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Image | |
BRC No. | RBRC11383 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S6-Mir124a-1hg<tm1Tfur> |
Former Common name | Rncr3<-/->, miR-124-1<-/-> |
H-2 Haplotype | |
ES Cell line | TC1 [129S6/SvEvTac] |
Background strain | |
Appearance | |
Strain development | Deposited by Takahisa Furukawa, Osaka University in 2021. This strain was generated using TC1/TC-1 (ES Cell) derived from 129S6/SvEvTac. Mice were further backcrossed to C57BL/6N for 5 generations. |
Strain description | Knockout mice for miR-124a-1. |
Colony maintenance | |
References | Nat. Neurosci., 14(9) 1125-34 (2011). doi: 10.1038/nn.2897. 21857657 Sci. Rep., 9(1) 3445 (2019). doi:10.1038/s41598-019-38910-2. 30837489 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Mir124a-1hgMir124-1 host gene (non-protein coding)14Mir124a-1hg<tm1Tfur>targeted mutation 1, Takahisa Furukawa Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)14mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signal14 |
Ordering Information | |
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Donor DNA | Mouse PGK promoter, E. coli Neomycin resistance gene, SV40 PolyA signal, Mouse Rncr3 locus |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature Neuronscience vol. 14,9 1125-34. 21 Aug. 2011,doi: 10.1038/nn.2897 Scientific reports vol. 9,1 3445. 5 Mar. 2019, doi:10.1038/s41598-019-38910-2In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Prior to the requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contact the DEPOSITOR and contract an MTA with Osaka University. |
Depositor | Takahisa Furukawa (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |