Strain Data Sheet

RBRC11320

Strain Information

Image
BRC No.RBRC11320
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6J.D2-Gpnmb<R150X>/Jwada
Former Common nameGpnmb KO mouse
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Jun Wada, Okayama University in 2021.
Strain descriptionGpnmb<R150X> derived from DBA/2J was introduced to C57BL/6 by backcrossing for 10 generations.
Colony maintenance
References
Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis.
Akihiro Katayama, Atsuko Nakatsuka, Jun Eguchi, Kazutoshi Murakami, Sanae Teshigawara, Motoko Kanzaki, Tomokazu Nunoue, Kazuyuki Hida, Nozomu Wada, Tetsuya Yasunaka, Fusao Ikeda, Akinobu Takaki, Kazuhide Yamamoto, Hiroshi Kiyonari, Hirofumi Makino, Jun Wada
Sci. Rep., 5:16920 (2015). 26581806

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Gpnmb
MGI:1934765		glycoprotein (transmembrane) nmb6Gpnmb<R150X>
MGI:2177814		iris pigment dispersion
  • amyloidosis, primary localized cutaneous, 3(MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 5:16920 (2015).
    DepositorJun Wada (Okayama University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data