Strain Data Sheet

RBRC11320

Strain Information

Image
BRC No.RBRC11320
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6J.D2-Gpnmb<R150X>/Jwada
Former Common nameGpnmb KO mouse
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Jun Wada, Okayama University in 2021.
Strain descriptionGpnmb<R150X> derived from DBA/2J was introduced to C57BL/6 by backcrossing for 10 generations.
Colony maintenance
References
Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis.
Katayama A, Nakatsuka A, Eguchi J, Murakami K, Teshigawara S, Kanzaki M, Nunoue T, Hida K, Wada N, Yasunaka T, Ikeda F, Takaki A, Yamamoto K, Kiyonari H, Makino H, Wada J
Sci. Rep., 5:16920 (2015). 26581806

Health Report

Examination Date / Room / Rack2023/12/11Room:3-5Rack:B
2023/09/13Room:3-5Rack:B
2023/09/11Room:3-5Rack:B
2023/06/13Room:3-5Rack:B
2023/03/13Room:3-5Rack:B

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Gpnmbglycoprotein (transmembrane) nmb6Gpnmbiris pigment dispersion
  • amyloidosis, primary localized cutaneous, 3(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 5:16920 (2015).
    DepositorJun Wada (Okayama University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data