Strain Information | |
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Image | |
BRC No. | RBRC11320 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | B6J.D2-Gpnmb<R150X>/Jwada |
Former Common name | Gpnmb KO mouse |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Jun Wada, Okayama University in 2021. |
Strain description | Gpnmb<R150X> derived from DBA/2J was introduced to C57BL/6 by backcrossing for 10 generations. |
Colony maintenance | |
References | Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis. Katayama A, Nakatsuka A, Eguchi J, Murakami K, Teshigawara S, Kanzaki M, Nunoue T, Hida K, Wada N, Yasunaka T, Ikeda F, Takaki A, Yamamoto K, Kiyonari H, Makino H, Wada J Sci. Rep., 5:16920 (2015). 26581806 |
Health Report | |
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Examination Date / Room / Rack | 2023/12/11Room:3-5Rack:B 2023/09/13Room:3-5Rack:B 2023/09/11Room:3-5Rack:B 2023/06/13Room:3-5Rack:B 2023/03/13Room:3-5Rack:B |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Gpnmb | glycoprotein (transmembrane) nmb | 6 | Gpnmb | iris pigment dispersion |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 5:16920 (2015). |
Depositor | Jun Wada (Okayama University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |