Strain Information | |
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Image | |
BRC No. | RBRC11315 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Cadps2<tm1.1Ksak> |
Former Common name | Cadps2-flox knock-in mice |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | Deposited by Teiichi Furuichi, Tokyo University of Science in 2021. Mice were generated using RENKA ES cells. C57BL/6 genetic background |
Strain description | Cadps2 floxed mice. A pair of loxP flanks exon 6. |
Colony maintenance | |
References | J. Neurosci., 41(20):4524-4535 (2021). 33846232 J. Clin. lnvest., 117, 931-943 (2007) . 17380209 J. Neurosci., 27, 2472-2482 (2007). 17344385 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Cadps2Ca2+-dependent activator protein for secretion 26Cadps2<tm1.1Ksak>targeted mutation 1.1, Kenji Sakimur Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site6Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP |
Ordering Information | |
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Donor DNA | P1 Phage (class 1) loxP sites (M10287), Saccharomyces cerevisiae (class 1) FRT site(J01347.1), Mus musculus CAPS2/Cadps2 genomic DNA(NM_153163) |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Neurosci. 2021 May 19;41(20):4524-4535. doi: 10.1523/JNEUROSCI.3240-20.2021.Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Kenji Sakimura; sakimura@bri.niigata-u.ac.jp) using the Approval Form. |
Depositor | Teiichi furuichi (Tokyo University of Science) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |