Strain Information | |
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Image | |
BRC No. | RBRC11304 |
Type | CRISPR/Cas9 |
Species | Mus musculus |
Strain name | B6J.B6N-Chdh<em1Rmps> |
Former Common name | Chdh KO mouse |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Takeo Yoshikawa, RIKEN in 2021. This strain was generated by the CRISPR/Cas9. Mice were further backcrossed to C57BL/6J. C57BL/6J congenic line. |
Strain description | Chdh mutant mice deleting 43 bp shortly after translation initiation codon. |
Colony maintenance | |
References | EBioMedicine. 45, 432-446 (2019). 31255657 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | Streptococcus Pyogenes Cas9 nickase |
Research application | Metabolism Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EBioMedicine. 45, 432-446 (2019). |
Depositor | Takeo Yoshikawa (RIKEN CBS) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |