Strain Information | |
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Image | |
BRC No. | RBRC11162 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Xcr1<tm5(XCR1)Ksho> |
Former Common name | hXCR1-KI |
H-2 Haplotype | |
ES Cell line | JM8A3.N1 [C57BL/6N-A<tm1Brd>] |
Background strain | |
Appearance | |
Strain development | Developed by Tsuneyasu Kaisho, Research Center for Allergy and Immunologuy, RIKEN around 2010. |
Strain description | A chemokine receptor, XCR1, is a receptor for XCL1 and expressed dominantly in one dendritic cell subset. hXCR1-KI mice were generated by knocking a gene encoding human XCR1 into the murine XCR1 gene locus. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site9Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site9Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)9GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter XCR1chemokine (C motif) receptor 1 (human)9XCR1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)9herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | human XCR1 cDNA, Bos taurus bGHpolyA, P1 Phage loxP sites, Saccharomyces cerevisiae FRT sites, Polyoma virus, Enhancer (MC1), HSV TK promoter (MC1), Escherichia coli Neomycin resistant gene, HSV TK polyA signal, mouse Xcr1 genomic DNA |
Research application | Cre/loxP system FLP/frt system Immunology and Inflammation Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) |
Depositor | Tsuneyasu Kaisho (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |