Strain Data Sheet

RBRC11160

Strain Information

Image
BRC No.RBRC11160
TypeRecombinant Congenic
SpeciesMus musculus
Strain nameMcH/Mo-lpr/lpr-RA1
Former Common nameMcH/Mo/lpr-RA1
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Tetsuya Kodama, Tohoku University in 2020.
Strain description
Colony maintenance
References
Novel recombinant congenic mouse strain developing arthritis with enthesopathy.
Mori S, Tanda N, Ito M R, Oishi H, Tsubaki T, Komori H, Zhang M C, Ono M, Nishimura M, Nose M
Pathol. Int., 58(7):407-14 (2008). 18577108

McH-lpr/lpr-RA1 mice: A novel spontaneous mouse model of autoimmune sialadenitis.
Saito K, Mori S, Kodama T
Immunol. Lett., 237:3-10 (2021). 34174253

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Fas
MGI:95484		Fas cell surface death receptor19Fas<lpr>
MGI:1856334		lymphoproliferation
  • autoimmune lymphoproliferative syndrome type 1(DisGeNET, MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationApoptosis Research
    Immunology and Inflammation Research
    Mouse Models for Human Disease
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Pathol. Int., 58(7):407-14 (2008). Immunol. Lett., 237:3-10 (2021).
    DepositorTetsuya Kodama (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data