Strain Data Sheet

RBRC11119

Strain Information

Image
BRC No.RBRC11119
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-Tlx1<tm2.1Rygo>
Former Common nameTlx1<fl>
H-2 Haplotype
ES Cell lineEGR-101 [C57BL/6N]
Background strain
Appearance
Strain developmentEGR-101 C57BL/6 strain-derived ES cells provided by Dr. M.Okabe of Osaka University.Homozygote x Homozygote [or Crossing to C57BL/6JJmsSlc]
Strain descriptionTlx1遺伝子の翻訳開始コドンを含む第一エキソン前後にloxP配列を有し、Cre活性化によりコンディショナルにTlx1遺伝子を欠損させることが可能である。
Colony maintenance
ReferencesSci. Rep., 8, 1-16 (2018). 29844356

Health Report

Examination Date / Room / Rack2023/11/27Room:4-BRack:E
2023/08/30Room:4-BRack:E
2023/08/28Room:4-BRack:E
2023/05/29Room:4-BRack:E
2023/03/22Room:4-BRack:E
2023/02/27Room:4-BRack:E
2022/11/29Room:4-BRack:E
2022/08/29Room:4-BRack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tlx1T cell leukemia, homeobox 119Tlx1<tm2.1Rygo>targeted mutation 2.1, Ryo Goitsuka

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site19Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Ordering Information

供与核酸phage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Tlx1 genomic DNA
Research applicationCre/loxP system
FLP/frt system
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Sci. Rep., 8, 1-16 (2018).
Depositor後飯塚　僚（東京理科大学）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結精子より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data