Strain Data Sheet

RBRC10853

Strain Information

Image
BRC No.RBRC10853
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Ctsc<tm1Ike>
Former Common nameCatC STOPtetO knockin
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain development生理研の池中一裕先生が新潟脳研の崎村建司先生との共同研究で作成。ESはRENKA(B6N)を使用。B6Nと交配して維持。Homozygoteで維持可能。生殖に問題なし。
Strain descriptionCathepsin C遺伝子の翻訳開始前にSTOP-tetOカセットがノックインしてある(Tanaka KF et al., Biol Psychiatry 2010, Shimizu T et al., Glia 2017)。ノックアウトマウスとして使用できる。
Colony maintenance
ReferencesGlia. 2017 Jun;65(6):917-930. 28251676

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ctsccathepsin C7Ctsc<tm1Ike>targeted mutation 1, Kazuhiro Ikenaka

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site7Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP7loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7mouse Phosphoglycerate kinase promoter (PGK promoter), synthetic bacterial EM7 promoter (T7 phage)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA signal7

Ordering Information

供与核酸マウス PGK プロモーター, synthetic bacterial EM7 promoter (T7 phage),トランスポゾン Tn5由来 Neo 耐性遺伝子, tetracycline operator site 酵母 His3 5’ UTR, FRT SV40 polyA シグナル CMV 最小プロモーター バクテリオファージP1 loxP
Research applicationCre/loxP system
FLP/frt system
Tet system
提供条件条件を付加しない。
Depositor大野 伸彦(生理学研究所)
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data