Strain Data Sheet
RBRC10747
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10747 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | C57BL/6-Rapgef3<tm1.2Ito> Rapgef4<tm1.1Ito> |
| Former Common name | CGIKO;CG2 KO |
| H-2 Haplotype | |
| ES Cell line | MS12 [C57BL/6] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Shigeyoshi Itohara at RIKEN. |
| Strain description | Double knockout for the genes, Rapgef3 and Rapgef4. Exon 1 and 2 or Exon 3 was deleted in Rapgef3 or Rapgef4 gene, respectively. |
| Colony maintenance | |
| References | |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2024/03/11Room:3-6Rack:B 2023/12/11Room:3-6Rack:B |
Gene | |
|---|---|
| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Rapgef3Rap guanine nucleotide exchange factor (GEF) 315Rapgef3<tm1.2Ito>targeted mutation 1.2, Shigeyoshi Itohara Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP15loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Rapgef4Rap guanine nucleotide exchange factor (GEF) 42Rapgef4<tm1.1Ito>targeted mutation 1.1, Shigeyoshi Itohara Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP |
Ordering Information | |
|---|---|
| Donor DNA | phage P1 loxP site, mouse Rapgef3 genomic DNA, mouse Rapgef4 genomic DNA |
| Research application | Cre/loxP system |
| Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
| Depositor | Shigeyoshi Itohara (RIKEN) |
| Strain Status |  Live mice Frozen sperm |
| Strain Availability | Cryopreserved sperm (within 1 month) Live mouse (3 to 6 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |