Strain Data Sheet

RBRC10746

Strain Information

Image
BRC No.RBRC10746
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Rapgef3<tm1.1Ito>
Former Common nameCGI flox
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development理化学研究所　脳神経科学研究センター・糸原重美らにより開発された。C57BL/6J(日本クレア)で維持。C57BL/6J由来。BAC clone ID：PR23-376L13
Strain descriptioncAMP-GEFIのexon1とexon2を挟んでloxP配列を挿入した遺伝子組換えマウス。Cre遺伝子の存在下で組換えをおこし、cAMP-GEFIのexon1とexon2をノックアウトすることが出来る。
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Rapgef3Rap guanine nucleotide exchange factor (GEF) 315Rapgef3<tm1.1Ito>targeted mutation 1.1, Shigeyoshi Itohara

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site15Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP15loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)15mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸マウス cAMP-GEFI, Pgk, P1ファージ LoxP, Yeast FRT, E.coli neo
Research applicationCre/loxP system
FLP/frt system
提供条件条件を付加しない。
Depositor糸原　重美（国立研究開発法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data