Strain Data Sheet

RBRC10701

Strain Information

Image
BRC No.RBRC10701
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-App<tm1.1(T668D)Ito>
Former Common nameT668D delta neo
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain development武田志津、佐野良威（糸原重美/鈴木利治）、APPリン酸化の生理機能を解析する為に作製。マウスAPP695の668番目のスレオニンをアスパラギン酸に置換B6のESで作製。C57BL/6J（日本クレア）と戻し交配。
Strain descriptionA mutant strain in which a threonine to aspartic acid mutation in codon 668 was introduced to the App gene.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Appamyloid beta (A4) precursor protein16App<tm1.1(T668D)Ito>targeted mutation 1, Shigeyoshi Itohara

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP16loxP

Ordering Information

供与核酸マウス Thr668Asp in App gene, P1ファージ LoxP配列
Research applicationCre/loxP system
Mouse Models for Human Disease
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。(will be announced.)
Depositor糸原　重美（国立研究開発法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data