Strain Data Sheet

RBRC10699

Strain Information

Image
BRC No.RBRC10699
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Apba2<tm1Tsuz>
Former Common nameX11L-KO
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain development佐野良威（糸原重美/鈴木利治）、X11Lの生理機能を解析する為に作製。B6のESで作製。C57BL/6由来のMS12細胞株。C57BL/6J　（日本クレア）と戻し交配。社会行動の低下。葛藤下で消極的な行動を示し、競争に負ける。マウスの生得的な行動の低下。
Strain descriptionApba2 (amyloid beta (A4) precursor protein-binding, family A, member 2; X11L) knockout mice. Homozygous mutants show reduced social interaction and tend to subordinated under competitive situation.
Colony maintenance
ReferencesJ. Biol. Chem., 281(49):37853-37860 (2006). 17032642

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Apba2amyloid beta (A4) precursor protein-binding, family A, member 27Apba2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP7loxP

Ordering Information

供与核酸マウス X11L, P1ファージ LoxP配列
Research applicationCre/loxP system
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。J. Biol. Chem., 281(49):37853-37860 (2006).
Depositor糸原　重美（国立研究開発法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data