Strain Information | |
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Image | |
BRC No. | RBRC10628 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Tgfbr2<tm1(cre/Esr1<*>)Sleep> |
Former Common name | Tgfbr2-CreERT2 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Yu Hayashi at University of Tsukuba and Shigeyoshi Itohara at RIKEN. ES cell line derived from C57BL/6J was used. C57BL/6J genetic background. |
Strain description | Knockin mice in which Cre/ERT2 was inserted at the translation initiation codon of the Tgfbr2 gene. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Tgfbr2transforming growth factor, beta receptor II9Tgfbr2<tm1(cre/Esr1<*>)Sleep>targeted mutation, Yu Hayashi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Actbchicken Beta-actin polyA9Actb Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Esr1*human Estrogen receptor9Esr1* Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site9Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter P2Aporcine teschovirus-1 2A peptide9P2A Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinase9cre |
Ordering Information | |
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Donor DNA | P2A (porcine teschovirus-1 2A peptide), Bacteriophage P1 Cre recombinase, Homo sapiens Estrogen receptor cDNA, chicken Beta-actin polyA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter, E. coli Neomycin resistance gene, mouse Tgfbr2 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Yu Hayashi (University of Tsukuba) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |