Strain Data Sheet

RBRC10612

Strain Information

Image
BRC No.RBRC10612
TypeTransgene and Spontaneous MutationCartagena
SpeciesMus musculus
Strain nameB6;Cg-Tg(Chn1)592Ito Chn1<mfy>/Ito
Former Common nameBAC-alpha Chn(Tg592):mfy/mfy
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. BAC TG was generated using fertilized eggs derived from (C57BL/6J x DBA) F2.
Strain descriptionA compound mouse strain harboring BAC transgene of the mouse Chn1 locus and the mfy mutation at the endogenous Chn1 locus.
Colony maintenance
References
Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling.
Takuji Iwasato, Hironori Katoh, Hiroshi Nishimaru, Yukio Ishikawa, Haruhisa Inoue, Yoshikazu M Saito, Reiko Ando, Mizuho Iwama, Ryosuke Takahashi, Manabu Negishi, Shigeyoshi Itohara
Cell, 130 (4), 742-753 (2007). 17719550

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Chn1
MGI:1915674		chimerin 12Chn1<mfy>
MGI:3760001		miffy
  • Duane retraction syndrome 2(MedGEN)
    • Frt yeast FRT (flippase recombination target) site2Frt
    loxP phage P1 loxP2loxP

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAマウス Chn1, P1-ファージ LoxP配列, 出芽酵母 FRT配列
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 130 (4), 742-753 (2007).
    DepositorShigeyoshi Itohara (RIKEN CBS)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data