Strain Data Sheet

RBRC10602

Strain Information

Image
BRC No.RBRC10602
TypeTransgene Congenic and Spontaneous MutationCartagena
SpeciesMus musculus
Strain nameB6;Cg-Tg(Chn1)883Ito Chn1<mfy>/Ito
Former Common nameBAC alpha Chn(Tg883):mfy/mfy
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. BAC TG was generated using fertilized eggs derived from (C57BL/6J x DBA) F2. Mice were further crossed with mfy mutant mice (B6 background).
Strain descriptionA compound mouse strain harboring BAC transgene of the mouse Chn1 locus and the mfy mutation at the endogenous Chn1 locus.
Colony maintenance
References
Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling.
Iwasato T, Katoh H, Nishimaru H, Ishikawa Y, Inoue H, Saito Y M, Ando R, Iwama M, Takahashi R, Negishi M, Itohara S
Cell, 130 (4), 742-753 (2007). 17719550

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Chn1
MGI:1915674		chimerin 12Chn1<mfy>
MGI:3760001		miffy
  • Duane retraction syndrome 2(MedGEN)
    • Frt yeast FRT (flippase recombination target) siteUNFrt
    loxP phage P1 loxPUNloxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAマウス Chn1, P1-ファージ LoxP配列, 出芽酵母 FRT配列
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 130 (4), 742-753 (2007).
    DepositorShigeyoshi Itohara (RIKEN CBS)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data