Strain Data Sheet

RBRC10448

Strain Information

Image
BRC No.RBRC10448
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Apba1<tm1Amor>/Tsuz
Former Common nameX11/mint 1 -KOマウス
H-2 Haplotype
ES Cell lineCCE28 [129/Sv]
Background strain
Appearance
Strain development開発者:大塚製薬入手経路:大塚製薬より供与譲渡後、C57BL/6J と10回以上back-cross。表現型:過敏行動。 -/-マウス同士の交配で繁殖可能であるが交配頻度は低く、出産後食殺多い。出産数少ない(3-5匹)。+/-の交配で繁殖。
Strain descriptionApba1 (amyloid beta (A4) precursor protein binding, family A, member 1; X11/mint 1) knockout mice. Homozygous mutants are fertile, but their littermate size is small (3 to 5 pups per litter). Heterozygous mice are used for breeding.
Colony maintenance
ReferencesNeurosci. Res., 43, 251-257 (2002). 12103443
J. Biol. Chem., 283, 35763-35771 (2008). 18845544

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Apba1amyloid beta (A4) precursor protein binding, family A, member 119Apba1<tm1Amor>targeted mutation 1, Atsushi Mori

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)19herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

供与核酸herpes simplex virus thymidine kinase prpmoter (MC1 prpmoter), E. coli neo, polyA, mouse Apba1 genomic DNA
Research application
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Neurosci. Res., 43, 251-257 (2002). J. Biol. Chem. 283, 35763-35771 (2008).
学術機関の学術研究に限る(製薬企業が作成したマウスであり学術研究だけの利用)。
Depositor鈴木 利治(国立大学法人北海道大学)
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結精子より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data