Strain Data Sheet
RBRC10261
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10261 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | B6J. Vb7 clone(iPS) |
| Former Common name | Vb7 clone |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Masaru Taniguchi, RIKEN Center for Integrative Medical Sciences in 2014. iPS cells were established by introducing Yamanaka factors into NKT cells derived from B6J spleen. Chimeric mice were generated and then backcrossed with C57BL/6J for 10 generations. |
| Strain description | Cloned mice harboring TCR chain, Vb7. |
| Colony maintenance | |
| References | Generation of induced pluripotent stem cell-derived mice by reprogramming of a mature NKT cell. Ren Y, Dashtsoodol N, Watarai H, Koseki H, Quan C, Taniguchi M Int. Immunol., 26(10), 551-561 (2014). 24854340 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 17 | Pou5f1 | ||||
| Sox2 | SRY (sex determining region Y)-box 2 | 3 | Sox2 | ||||
| Klf4 | Kruppel-like transcription factor 4 (gut) | 4 | Klf4 | ||||
| Retrovirus LTR | |||||||
| SV40 polyA | |||||||
| Nanog | Nanog homeobox | Nanog | |||||
| neo | neomycin resistance gene | mouse phosphoglycerate kinase promoter (PGK promoter) | |||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Retrovirus LTR, E. coli neomycin, SV40 Poly A, Mouse PGK promoter, Mouse Oct3/4, Mouse Klf-4, Mouse Sox-2, Mouse Nanog |
| Research application | Immunology and Inflammation Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Int. Immunol. ;26(10), 551-561, (2014). |
| Depositor | Masaru Taniguchi (RIKEN) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |