Strain Data Sheet
RBRC10257
Strain Information | |
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| Image | |
| BRC No. | RBRC10257 |
| Type | Other |
| Species | Mus musculus |
| Strain name | B6J.Va14, Vb8.1 clone(ES) |
| Former Common name | Va14, Vb8.1 clone |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Masaru Taniguchi, RIKEN Center for Integrative Medical Sciences in 2010. ES cells were established by the nuclear transfer of NKT cells into enucleated eggs derived from B6D2F1. Chimeric mice were generated and then backcrossed with C57BL/6J for 10 generations. |
| Strain description | Cloned mice harboring invariant TCR chains, Va14-Ja18 and Vb8.1. |
| Colony maintenance | |
| References | Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant Valpha14-Jalpha18 TCRalpha gene. Watarai H, Rybouchkin A, Hongo N, Nagata Y, Sakata S, Sekine E, Dashtsoodol N, Tashiro T, Fujii S, Shimizu K, Mori K, Masuda K, Kawamoto H, Koseki H, Taniguchi M Blood, 115(2), 230-237 (2010). 19897575 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Blood. 115(2), 230-237, (2010). |
| Depositor | Masaru Taniguchi (RIKEN) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |