Strain Information | |
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Image | |
BRC No. | RBRC10251 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C.129-Klre1<tm1Tgi> |
Former Common name | NKG2I KO |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | BALB/cAnNCrlCrlj |
Appearance | |
Strain development | Developed by Masaru Taniguchi, RIKEN Center for Integrative Medical Sciences in 2004. R1 ES cells were used. This line was backcrossed with BALB/c for 10 generations. |
Strain description | Klre1 (killer cell lectin-like receptor family E member 1) knockout mice. Homozygous mutants display impaired natural killer cell mediated allogeneic cytotoxicity. EGFP is placed downstream of translation initiation codon. |
Colony maintenance | |
References | Blood, 104, 781-783 (2004). 15069013 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/05Room:2-検Rack:F |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Klre1killer cell lectin-like receptor family E member 16Klre1<tm1Tgi>targeted mutation 1, Masaru Taniguchi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)6EGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Aequorea victoria EGFP cDNA, Phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Klre1 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Blood 104:781-783, (2004). |
Depositor | Masaru Taniguchi (RIKEN) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Live mouse (more than 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |