Strain Information | |
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Image | |
BRC No. | RBRC10238 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6;Cg-Tg(Cryd1/Cryaa-Sfrp2)1Jmca |
Former Common name | Sfrp2 lens (M2) |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Transgenic construct was injected into BCBF1 (C57/BL6xCBA) embryos. Generated by John McAvoy laboratory in the University of Sydney.After backcrossing to C57/BL6 line for a few generations, the line has been maintained as inbred.Small lens formation. Cataract development.Mice can be maintained as heterozygous or homozygous. |
Strain description | Transgenic mouse line with Sfrp2 (secreted frizzled related protein-2) overexpression in lens. |
Colony maintenance | |
References | Development Biology, 324, 161-176 (2008). 18824165 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (human)UNGH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Sfrp2secreted frizzled-related protein 2UNSfrp2Chicken delta 1-crystallin (ASL1) enhancer and promoter, Mouse alpha A-crystallin (Cryaa) promoter, Rabbit beta-globin intron |
Ordering Information | |
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供与核酸 | Chicken delta 1-crystallin (ASL1) enhancer and promoter, Mouse alpha A-crystallin (Cryaa) promoter, Rabbit beta-globin intron, Mouse Sfrp2 coding region, Human growth hormone poly A |
Research application | Developmental Biology Research |
提供条件 | 条件を付加する。 研究成果の公表にあたって寄託者の指定する文献を引用する。Development Biology, 324, 161-176 (2008). 研究成果の公表にあたって謝辞の表明を必要とする。 For use of the BIOLOGICAL RESOURCE by a for-profit organization, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | 杉山 由樹(学校法人沖縄科学技術大学院大学(OIST)) |
Strain Status | 凍結胚 凍結精子 |
Strain Availability | 凍結精子より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |