Strain Data Sheet
RBRC10167
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10167 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6.Cg-Gprc5c<tm1Yhir> |
| Former Common name | GPRC5C-deficient, (Acc. No. CDB0485K) |
| H-2 Haplotype | |
| ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
| Background strain | |
| Appearance | |
| Strain development | (C57BL/6NCrlj x CBA/JNCrlj)F1, TT2 (ES 細胞)を用いて作出。C57BL/6J コンジェニック系統。兄妹交配にて維持。明確な表現型変動は見られない。RIKEN CDBが作製（Acc. No. CDB0485K）。https://large.riken.jp/distribution/mutant-list.html |
| Strain description | GPRC5CはClass Cに属するorphan G protein-coupled receptorの一種である。 |
| Colony maintenance | |
| References | Biochem. Biophys. Res. Commun., 412(3), 460-465 (2011). 21840300 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2024/01/09Room:3-ARack:G 2023/10/16Room:3-ARack:G 2023/10/10Room:3-ARack:G 2023/07/10Room:3-ARack:G 2023/04/10Room:3-ARack:G 2023/02/13Room:3-ARack:G 2023/01/10Room:3-ARack:G 2022/10/11Room:3-ARack:G 2022/07/11Room:3-ARack:G |
Gene | |
|---|---|
| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gprc5cG protein-coupled receptor, family C, group 5, member C11Gprc5c<tm1Yhir>targeted mutation 1, Yoshio Hirabayashi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site11Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site11Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA7 |
Ordering Information | |
|---|---|
| 供与核酸 | Phage P1 lox71 site, Phage P1 loxP site, E. coli lacZ gene, yeast FRT (flippase recombination target) sites, Mouse Phosphoglycerate kinase promoter, E. coli Neomycin resistance gene, SV40 PolyA signal, mouse Gprc5c genomic DNA |
| Research application | Cre/loxP system FLP/frt system Fluorescent Proteins/lacZ System |
| 提供条件 | 条件を付加する。 学術機関の学術研究に限る。営利機関の利用希望者は、事前に利用条件等につき寄託者と合意し、提供承諾を得ること。 |
| Depositor | 平林 義雄（国立研究開発法人理化学研究所） |
| Strain Status |  凍結胚 凍結精子 |
| Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |