Strain Information | |
---|---|
Image | |
BRC No. | RBRC10083 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Map3k5<tm3.1Hijo> |
Former Common name | Ask1 flox/flox, Map3k5 flox/flox |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Hidenori Ichijo, Graduate School of Pharmaceutical Sciences, The University of Tokyo. ENKA (C57BL/6) ES cells were used. C57BL/6 genetic background. |
Strain description | Floxed Map3k5 (mitogen-activated protein kinase kinase kinase 5、ASK1) mice. Exon 15 was flanked by loxP sites. |
Colony maintenance | |
References | Nat. Commun., 7:11158 (2016). doi: 10.1038/ncomms11158. 27045525 Kamiyama et al, 2017 accepted 28753204 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Map3k5mitogen-activated protein kinase kinase kinase 510Map3k5<tm3.1Hijo>targeted mutation 3.1, Hidenori Ichijo Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site10Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP |
Ordering Information | |
---|---|
Donor DNA | Phage P1 loxP sites, Saccharomyces cerevisiae FRT site, mouse Map3k5 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Hidenori Ichijo (The University of Tokyo) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |