Strain Data Sheet

RBRC10006

Strain Information

Image
BRC No.RBRC10006
TypeCongenic
SpeciesMus musculus
Strain nameFVB.ICR-Pde6b<+>/Daiw
Former Common nameFVB rd (+/+)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice.
Gimenez E, Montoliu L
Lab Anim., 35(2):153-6 (2001). 11315164

The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia.
Watanabe D, Saijoh Y, Nonaka S, Sasaki G, Ikawa Y, Yokoyama T, Hamada H
Development, 130, 1725-1734 (2003). 12642479

Multiple renal cyst development but not situs abnormalities in transgenic RNAi mice against Inv::GFP rescue gene.
Kamijho Y, Shiozaki Y, Sakurai E, Hanaoka K, Watanabe D
PLoS One, 9(2):e89652 (2014). 24586938

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pde6b
MGI:97525		phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide5Pde6b
  • congenital stationary night blindness autosomal dominant 2(DisGeNET, MedGEN)

  • retinitis pigmentosa 40(DisGeNET, MedGEN)

  • retinitis pigmentosa(DisGeNET)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 130, 1725-1734 (2003). The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in case of application for any patents or for-profit use based o the results from the use of the BIOLOGICAL RESOURCE.
    DepositorDaisuke Watanabe (Kitasato University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data