Strain Data Sheet

RBRC09601

Strain Information

Image
BRC No.RBRC09601
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Ccdc86<tm1Hfuj>
Former Common nameCyclon-KO(EN)
H-2 Haplotype
ES Cell lineiTL IC1 [C57BL/6NTac]
Background strain
Appearance
Strain development開発者／機関：藤井　穂高／ニューヨーク大学。開発年：2009年。iTL IC1 ES細胞 [C57BL/6NTac]を使用。C57BL/6背景。
Strain descriptionCcdc86 (coiled-coil domain containing 86, 別名Cyclon) 欠損マウス。エキソン１の翻訳開始点下流にEnhanced Green Fluorescent Protein (EGFP) 遺伝子とネオマイシン耐性遺伝子が挿入されている。ヘテロ型は活性化T細胞におけるFas蛋白質の発現が低下している。ホモ型は胎生期／周産期致死 (どの時期かは不明) 。
Colony maintenance
ReferencesBlood, 13;114(7), 1355-1365 (2009). 19528538

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ccdc86coiled-coil domain containing 8619Ccdc86<tm1Hfuj>targeted mutation 1, Hodaka Fujii4933411H20Rik, 6720480F16Rik, cyclon, D19Ertd678e

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)19EGFP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP19loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)19mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸P1ファージ　loxP, オワンクラゲ Green Fluorescent Protein (GFP)(緑色蛍光蛋白質), マウス　Cyclon蛋白質遺伝子, マウス phosphoglycerate-kinase 1 (pgk) プロモーター, 大腸菌　ネオマイシン耐性遺伝子
Research applicationCre/loxP system
Fluorescent Proteins/lacZ System
提供条件条件を付加する。
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon. Saint Fleur S, Hoshino A, Kondo K, Egawa T, Fujii H. Blood (2009) 114 (7): 1355-65. The BIOLOGICAL RESOURCE shall be used only for academic research purposes by not-for-profit institutions. Use of the BIOLOGICAL RESOURCE by for-profit institutions or use for commercial research purposes shall require a commercial license from the Depositor. A recipient shall also acquire a prior written consent from the Depositor prior to filing an application for a patent, or intellectual property or other rights based on the results of their use of the BIOLOGICAL RESOURCE.
Depositor藤井　穂高（New York University School of Medicine）
Strain Status凍結精子のアイコン凍結精子
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data