Strain Information | |
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Image | |
BRC No. | RBRC09487 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6N-Tyr<c-Brd>-Tg(IL6-Luc) |
Former Common name | hIL6-BAC-Luc |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice. Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M Mol. Cell Biol., 35(20):3590-601 (2015). 26283726 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Frt | yeast FRT (flippase recombination target) site | 7 | Frt | ||||
Tyr | tyrosinase | 7 | Tyr | albino, Allan Bradley | |||
SV40 polyA | UN | ||||||
loxP | phage P1 loxP | UN | loxP | ||||
luc | luciferase | UN | luc | human IL6 promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | human IL6 locus genomic DNA (BAC clone RP11-469J8), firefly luciferase cDNA, SV40 late polyA signal, yeast FRT (flipase recombination target) site, Phage P1 loxP site |
Research application | Cre/loxP system FLP/frt system Immunology and Inflammation Research covid19_onset |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell Biol., 35(20):3590-601 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, involving the DEPOSITOR in author byline is requested (by Aug 2017). |
Depositor | Masayuki Yamamoto (Tohoku University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month May 2016 |
BRC mice in Publications |
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No Data |