Strain Data Sheet

RBRC06578

Strain Information

Image
BRC No.RBRC06578
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Tg(CAG-LNL-Adipo)1Shb
Former Common nameLNL-Adiponectin Tg, B6-LNLAdipo Tg
H-2 Haplotype
ES Cell line
Background strainC57BL/6NCrSlc
Appearance
Strain developmentDeveloped by Kiyomi Saito, School of Pharmaceutical Sciences, Showa University in 2005. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs.
Strain descriptionAdniponetcin conditional transgenic mice.
Colony maintenanceCarrier x Carrier, Noncarrier [or Crossing to C57BL/6NCrSlc]
References
Adiponectin plays an important role in efficient energy usage under energy shortage.
Saito K, Arata S, Hosono T, Sano Y, Takahashi K, Choi-Miura N H, Nakano Y, Tobe T, Tomita M
Biochim. Biophys. Acta., 1761. 709-716 (2006). 16815093

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Adipoqadiponectin, C1Q and collagen domain containingUNAdipoq
loxPphage P1 loxPUNloxPCAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
loxPphage P1 loxPUNloxP
neoneomycin resistance gene (E. coli)UN
poly Apolyadenylic acid additional signalUNpoly A

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
  • Detailed phenotype data

    Ordering Information

    Donor DNACMV IE enhancer, chicken beta-actin promoter, rabbit beta-globin gene 3’-flanking sequence, phage P1 loxP, E. coli neomycin resistance gene, mouse adiponectin cDNA
    Research applicationCre/loxP system
    Diabetes and Obesity Research
    Hematological Research
    Immunology and Inflammation Research
    covid19_infection
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochim Biophys Acta., 1761, 709-716 (2006).For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorYasuko Nakano (Showa University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. CAGGS MTA (English)
    5. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data