Strain Information | |
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Image | |
BRC No. | RBRC06578 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6N-Tg(CAG-LNL-Adipo)1Shb |
Former Common name | LNL-Adiponectin Tg, B6-LNLAdipo Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrSlc |
Appearance | |
Strain development | Developed by Kiyomi Saito, School of Pharmaceutical Sciences, Showa University in 2005. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs. |
Strain description | Adniponetcin conditional transgenic mice. |
Colony maintenance | Carrier x Carrier, Noncarrier [or Crossing to C57BL/6NCrSlc] |
References | Adiponectin plays an important role in efficient energy usage under energy shortage. Saito K, Arata S, Hosono T, Sano Y, Takahashi K, Choi-Miura N H, Nakano Y, Tobe T, Tomita M Biochim. Biophys. Acta., 1761. 709-716 (2006). 16815093 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Adipoq | adiponectin, C1Q and collagen domain containing | UN | Adipoq | ||||
loxP | phage P1 loxP | UN | loxP | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) | |||
loxP | phage P1 loxP | UN | loxP | ||||
neo | neomycin resistance gene (E. coli) | UN | |||||
poly A | polyadenylic acid additional signal | UN | poly A |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | CMV IE enhancer, chicken beta-actin promoter, rabbit beta-globin gene 3’-flanking sequence, phage P1 loxP, E. coli neomycin resistance gene, mouse adiponectin cDNA |
Research application | Cre/loxP system Diabetes and Obesity Research Hematological Research Immunology and Inflammation Research covid19_infection |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochim Biophys Acta., 1761, 709-716 (2006).For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Yasuko Nakano (Showa University) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |