Strain Information | |
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Image | |
BRC No. | RBRC06553 |
Type | Transgene![]() |
Species | Mus musculus |
Strain name | B6.Cg-Tg(RAREn-hsp-lacZ)3Hmd |
Former Common name | RAREn-hsp-lacZ(3), B6-RAREn-lacZ Tg#3 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Katsuyoshi Takaoka and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2012. The transgene was injected into the pronuclei of B6C3F2 fertilized eggs. C57BL/6 and C3H mixed background. |
Strain description | 9xRAREn-hsp-lacZ transgenic mice. Line 3 (RBRC06553), Line 5 (RBRC06554). |
Colony maintenance | Carrier x Noncarrier [or Crossing to C57BL/6JJcl] |
References | Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning. Uehara M, Yashiro K, Takaoka K, Yamamoto M, Hamada H Genes Dev., 23, 1689-1698 (2009). 19605690 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Nodal | mouse Nodal retinoic acid response element (RAREn) | UN | Nodal | ||||
lacZ | beta-galactosidase (E. coli) | UN | mouse hsp68 promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse Nodal retinoic acid response element (RAREn) genomic DNA, mouse hsp68 promoter, E. coli lacZ |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev., 23, 1689-1698 (2009). |
Depositor | Hiroshi Hamada (RIKEN CDB) |
Strain Status | ![]() |
Strain Availability | ![]() |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |