Strain Information | |
---|---|
Image | |
BRC No. | RBRC06540 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Dchs2<tm1.2Hmd> |
Former Common name | Dachsous2 delta ex29, B6-Dchs2 KO |
H-2 Haplotype | |
ES Cell line | G4 [(129S6/SvEvTac x C57BL/6NCr)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Katsura Minegishi and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2012. G4 ES cells derived from (129 x C57BL/6)F1 were used to generate the mutant mice. Flanked Exon 29 was removed by crossing with CAG-Cre mice (B6/129 background). C57BL/6 and 129 mixed background. |
Strain description | Exon 29 of Dchs2 (dachsous 2) gene was removed. Homozygous mutant mice are viable and fertile. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6JJcl] |
References | Development, 149(9):dev200315 (2022). doi: 10.1242/dev.200315 35420656 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP3loxP |
Ordering Information | |
---|---|
Donor DNA | phage P1 loxP site, mouse Dchs2 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 149(9):dev200315 (2022). |
Depositor | Hiroshi Hamada (RIKEN CDB) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |