Strain Data Sheet



BRC No.RBRC06419
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameKOR1.Cg-Dms
Former Common nameKOR.DMS, KOR1-Dms
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain descriptionDiabetes Mellitus Saitama, DMS. Spontaneous mutation arose in NC/Jic x KOR1 F2 generations. Heterozygous mutant mice show type 2 diabetes. Homozygous mutant mice show lethal neonatal diabetes. Under investigation (details unknown). AKR background (semicongenic) (RBRC06413), C57BL/6 background (semicongenic) (RBRC06414), BALB/c background (semicongenic) (RBRC06415), C3H background (semicongenic) (RBRC06416), DBA/2 background (semicongenic) (RBRC06417), JF1 background (semicongenic) (RBRC06418), KOR1 background(semicongenic) (RBRC06419), NC background(semicongenic) (RBRC06420).
Colony maintenanceHeterozygote x Wild-type [or Crossing to KOR1/Stm (RBRC00427)]

Health Report

Examination Date / Room / Rack2021/09/13Room:4-CRack:G


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Insrinsulin receptor8Insr<Dms>diabetes mellitus saitama


Donor DNA
Research applicationDiabetes and Obesity Research
Mouse Models for Human Disease
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data