Strain Data Sheet
RBRC06419
Information1 | |
|---|---|
| Image | |
| BRC No. | RBRC06419 |
| Type | Spontaneous Mutation |
| Species | Mus musculus |
| Strain name | KOR1.Cg-Dms |
| Former Common name | KOR.DMS, KOR1-Dms |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology. |
| Strain description | Diabetes Mellitus Saitama, DMS. Spontaneous mutation arose in NC/Jic x KOR1 F2 generations. Heterozygous mutant mice show type 2 diabetes. Homozygous mutant mice show lethal neonatal diabetes. Under investigation (details unknown). AKR background (semicongenic) (RBRC06413), C57BL/6 background (semicongenic) (RBRC06414), BALB/c background (semicongenic) (RBRC06415), C3H background (semicongenic) (RBRC06416), DBA/2 background (semicongenic) (RBRC06417), JF1 background (semicongenic) (RBRC06418), KOR1 background(semicongenic) (RBRC06419), NC background(semicongenic) (RBRC06420). |
| Colony maintenance | Heterozygote x Wild-type [or Crossing to KOR1/Stm (RBRC00427)] |
| References | |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2021/09/13Room:4-CRack:G 2021/06/14Room:4-CRack:G |
Gene | |
|---|---|
| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Information2 | |
|---|---|
| Donor DNA | |
| Research application | Diabetes and Obesity Research Mouse Models for Human Disease covid19_progression |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
| Depositor | Yoshibumi Matsushima (Saitama Cancer Center) |
| Strain Status |  Frozen embryos |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
| No Data |