Strain Information | |
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Image | |
BRC No. | RBRC06357 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Msr1<tm1(HBEGF)Mtka> |
Former Common name | CD204-DTR, B6-Msr1/DTR KI |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Masato Tanaka, RIKEN Research Center for Allergy and Immunology in 2011. B6JN/1 ES cells were used. C57BL/6 background. |
Strain description | CD204 (Msr1) DTR knock-in mice. HB-EGF is expressed from CD204 locus. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6JJcl] |
References | Biochem Biophys Rep. Aug 7;23:100791 (2020). doi: 10.1016/j.bbrep.2020.100791. eCollection 2020 Sep. 32793817 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site8Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBB2rabbit beta-globin polyA8HBB2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBEGFheparin-binding EGF-like growth factor (human)8HBEGF Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter gb2phage T7 gb2 promoter(synthetic)8gb2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)8mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | human HB-EGF gene cDNA, Rabbit beta-globin polyA, Saccharomyces cerevisiae FRT sites, mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter, E. coli Neomycin resistance gene, mouse Msr1 genomic DNA |
Research application | FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem Biophys Rep. 2020 Aug 7;23:100791. doi: 10.1016/j.bbrep.2020.100791. eCollection 2020 Sep.The recipient shall not distribute the biological resource to others without a written consent from the DEPOSITOR. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR/DEVELOPER (Masato Tanaka and Gen Nishitai), and then include them as co-authors in any publications resulted by the use of the BIOLOGICAL RESOURCE. |
Depositor | Masato Tanaka (Tokyo University of Pharmacy and Life Sciences) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |