Strain Data Sheet

RBRC06233

Information1

Image
BRC No.RBRC06233
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameDS/Shi-Trpv3<Nh>/Shi
Former Common nameDS-Nh
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Shionogi & Co., Ltd. Arose in DS mouse that has been established as an inbred strain from a dd closed colony mice.
Strain descriptionNon-hair dominant spontaneous mutant mice arose in DS/Shi inbred souse strain. A G1717A point mutation has been found in the Trpv3, which results in Gly 573 being replaced with Ser. Coisogenic strain (RBRC06233), C57BL/6J (C57BL/6JShi) congenic (RBRC06234) and BALB/c (BALB/cMsShi) congenic (RBRC06235).
Colony maintenanceWild-type (female) x Heterozygote (male) [or Crossing to DS/Shi(RBRC03706)]
ReferencesJ. Invest. Dermatol., 129, 714-722 (2009). 18754035
J. Invest. Dermatol., 126, 2664-2672 (2006). 16858425
Immunology, 118, 293-301 (2006). 16827890
J. Dermatol. Sci., 30, 142-153 (2002). 12413770
Exp. Anim., 46, 225-229 (1997). 9250484
Exp. Anim., 52, 77-80 (2003). 12638241
Immunology. 108, 562-569 (2003). 12667219
Exp. Anim., 52, 419-423 (2003). 14625409

Health Report

Examination Date / Room / Rack2022/05/31Room:4-BRack:G
2022/03/07Room:4-BRack:G
2021/12/06Room:4-BRack:G
2021/09/08Room:4-BRack:G
2021/06/07Room:4-BRack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Trpv3transient receptor potential cation channel, subfamily V, member 311Trpv3<Nh>non-hair

Information2

Donor DNA
Research applicationImmunology and Inflammation Research
Mouse Models for Human Disease
Sensorineural Research
Specific Term and Conditions1) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. 2) The RECIPIENT must inform the DEPOSITOR the research plan using the BIOLOGICAL RESOURCE and must obtain a prior written consent form the DEPOSITOR using the APPROVAL FORM specified by the DEPOSITOR. 3) The RECIPIENT shall use the BIOLOGICAL RESOURCE exclusively for the purpose of research which was written in the research plan. 4) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must inform the DEPOSITOR of the contents of such publication in advance. 5) The RECIPIENT contact and discuss with the DEPOSITOR in case of filing a patent application based on research results by using the BIOLOGICAL RESOURCES. 6) The RECIPIENT must contact and discuss with the DEPOSITOR in case of application for any commercial use.
DepositorKiyoshi Yasui (Shionogi & Co., Ltd)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data