Strain Data Sheet

RBRC06182

Strain Information

Image
BRC No.RBRC06182
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S2.129(B6)-Thrb<tm1Olc>/Sasu
Former Common nameＴＲβ-/-, 129-Thrb KO
H-2 Haplotype
ES Cell lineENS [129/Sv]
Background strain129S2/SvPas
Appearance
Strain developmentEcole Normale Superieure de Lyon・Olivier Chassande、Jacques Samarutらにより開発。ENS ES細胞（129/Sv）を用いて作出。
Strain description甲状腺ホルモン核受容体βアイソフォーム1と2の欠損マウス。Thra遺伝子のエクソン4と5がlacZ-neoカセットで置換されている。
Colony maintenanceHomozygote x Homozygote
ReferencesEMBO J., 18, 623-631 (1999). 9927422

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Thrbthyroid hormone receptor beta14Thrb<tm1Olc>targeted mutation 1, Olivier Chassande

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
lacZbeta-galactosidase (E. coli)14

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)14

Ordering Information

供与核酸E. coli Neomycin resistance gene, E. coli beta-galactosidase, mouse Thra genomic DNA
Research applicationFluorescent Proteins/lacZ System
提供条件条件を付加しない。
Depositor鈴木　悟（公立大学法人福島県立医科大学）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data