Strain Data Sheet


Strain Information

BRC No.RBRC06140
SpeciesMus musculus
Strain nameC57BL/6-Tg(Fabp4-Serpina12)10
Former Common nameVaspin Tg#10, B6-Serpina12 Tg#10
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Jun Wada, Department of Medicine and Clinical Science, Okayama University and Yoichiro Iwakura, Institute of Medical Sciences, University of Tokyo in 2005. C57BL/6J background.
Strain descriptionVaspin (Serpina12) gene transgenic mice. These mice express the mouse Vaspin gene under the control of the aP2 promoter. Tg mice are protected from diet-induced obesity, glucose intolerance, and hepatic steatosis.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
ReferencesCirc Res., 112, 771-780 (2013). 23307819
Diabetes, 61, 2823-2832, (2012). 22837305

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
GHGrowth hormone polyA (human)UNGH

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HBB2rabbit beta-globin intronUNHBB2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Serpina12serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12UNSerpina12mouse fatty acid binding protein 4, adipocyte promoter

Ordering Information

Donor DNAMouse aP2 promoter, Mouse SERPINA12 (vaspin) gene cDNA, Rabbit beta-Globin intron, Human GH polyA signal
Research applicationApoptosis Research
Diabetes and Obesity Research
Hematological Research
Metabolism Research
Mouse Models for Human Disease
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorJun Wada (Okayama University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data