Strain Data Sheet
RBRC06077
Strain Information | |
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| Image | |
| BRC No. | RBRC06077 |
| Type | Gene Trap Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Elovl6<Gt(Ayu21-W126*mERT2)1Card> |
| Former Common name | Elovl6-mERT2,61, B6-Elovl6/CreER Gt#1 |
| H-2 Haplotype | |
| ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Masatake Araki, Institute of Molecular Embryology and Genetics, Kumamoto University. KTPU8 ES cells were used. C57BL/6 and CBA mixed. |
| Strain description | Elovl6-creER driver mice. The beta-geo gene in the exchangeable gene trap clone of Elovl6 gene was replaced with a mERT2. |
| Colony maintenance | Heterozygote x Wild-type [C57BL/6NJcl] |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Elovl6 MGI:2156528 | ELOVL fatty acid elongase 6 | 3 | Elovl6<Gt(Ayu21-W126*mERT2)1Card> | gene trap 1, Center for Animal Resources & Development | |||
| En2 | En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence) | 3 | En2 | ||||
| Ert2 | estrogen receptor (mouse) | 3 | Ert2 | ||||
| Frt | yeast FRT (flippase recombination target) site | 3 | Frt | ||||
| cre | Phage P1 Cre recombinase | 3 | cre | ||||
| loxP | phage P1 loxP | 3 | loxP | ||||
| loxP | phage P1 loxP | 3 | loxP | ||||
| nls | SV40 large T antigen nuclear localization signal (NLS) | 3 | nls | ||||
| polyA | mouse PGK | 3 | polyA | ||||
| puro | puromycin acyltransferase (Streptomyces alboniger) | 3 | puro | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | mouse En2 splice acceptor, mouse PGK promoter, mouse PGK polyA signal, Streptomyces alboniger puromycin resistance gene, phage P1 cre recombinase, mouse estrogen receptor, yeast FRT (flipase recombination target) site, phage P1 loxP and mutant lox sequence, E. coli pSP73 vector sequence, mouse Elovl6 genomic DNA |
| Research application | Cre/loxP system |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. will be announced.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Masatake Araki (Kumamoto University) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |