Strain Information | |
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Image | |
BRC No. | RBRC06009 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | ICR.Cg-Hes5<tm1(Eluc)Imayo> |
Former Common name | Eluc-Hes5 fusion Knock-in ; Hes5/Eluc KI |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Itaru Imayoshi and Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2010. TT2 ES cells were used. The mutant mice were crossed to ICR. |
Strain description | Eluc/Hes5 knock-in mice. Eluc-Hes5 fusion protein is expressed from Hes5 locus. |
Colony maintenance | Heterozygote x Wild-type [or Crossing to Slc:ICR] |
References | Science, 342(6163):1203-8. doi: 10.1126/science.1242366. 24179156 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Hes5hairy and enhancer of split 5 (Drosophila)4Hes5<tm1(Eluc)Imayo>targeted mutation 1, Itaru Imayoshi |
Ordering Information | |
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Donor DNA | Eluc (synthetic), Yeast Frt (flippase recombination target) site, mouse Hes5 genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science DOI: 10.1126/science.1242366In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp) and Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Ryoichiro Kageyama and Itaru Imayoshi (Kyoto University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |