Strain Information | |
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Image | |
BRC No. | RBRC05925 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-Smap2<tm1Sata> |
Former Common name | SMAP2 KO |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | eveloped by Masanobu Satake, Institute of Development, Aging and Cancer, Tohoku University and Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo. E14 ES cells were used. The mutant mice were backcrossed to C57BL/6J. |
Strain description | Smap2 gene knockout mice. Homozygous mutant males exhibit hypoplastic acrosome and are infertile due to globozoospermia. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] Homozygous mutant males are infertile. |
References | Mol. Biol. Cell, 17, 2592-2603 (2006). 16571680 Cell Struct. Funct., 36, 83-95 (2011). 21368446 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Smap2stromal membrane-associated GTPase-activating protein 24Smap2<tm1Sata>targeted mutation 1, Masanobu Satake Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)4 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4 |
Ordering Information | |
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Donor DNA | Mouse SMAP2 genome, E. coli Beta-galactosidase, E. coli Neomycin resistance gene |
Research application | Cell Biology Research Developmental Biology Research Fluorescent Proteins/lacZ System |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Masanobu Satake (Tohoku University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |