Strain Information | |
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Image | |
BRC No. | RBRC05899 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(CAG-MacroH2A/EGFP)01Tois |
Former Common name | MacoH2A-EGFP, B6-CAG-MacroH2A/GFP Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Tomoko Nakanishi, Faculty of Medicine, Tottori University in 2009. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mutant mice were crossed to C57BL/6. |
Strain description | MacroH2A-EGFP transgenic mice. This transgenic mice express the mouse MacroH2A1.2-EGFP under the control of a CAG promoter. |
Colony maintenance | Carrier x Noncarrier [C57BL/6NCrSlc] |
References | Visualization of inactive X chromosome in preimplantation embryos utilizing MacroH2A-EGFP transgenic mouse. Soma A, Sato K, Nakanishi T Genesis, 51(4):259-67 (2013). doi: 10.1002/dvg.22369. 23349035 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
EGFP | Enhanced Green Fluorescent Protein (Aequorea victoria) | UN | EGFP | ||||
MacroH2A | MacroH2A | UN | MacroH2A | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Cytomegalovirus Immediate-early enhancer, Chicken Beta actin promoter, Mouse MacroH2A1.2, Aequorea victoria Green fluorescent protein, Rabbit Beta globin polyA signal |
Research application | Developmental Biology Research Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genesis. 2013 Jan 24. doi: 10.1002/dvg.22369. |
Depositor | Tomoko Nakanishi (Tottori University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |