Strain Information | |
---|---|
Image | |
BRC No. | RBRC05849 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Dkk3<tm1.1> |
Former Common name | C57BL/6J-Dkk3 KO(wt/KO/Cre), Dkk3 KO(wt/KO/Cre) |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Developed by Masaki Watabe and Hiromi Kumon, Okayama University Graduate School of Medicine and Kazuhiko Ochiai, Faculty of Veterinary Science, School of Veterinary Nursing and Technology. Bruce4 ES cells were used. Exon 5 to 6 and PGK-neo cassette were removed by crossing with a Cre mice (B6 background). |
Strain description | REIC/Dkk3 gene knockout mice. Exons 5 and 6 were removed. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6J(Crlj)]Homozygous mutant mice are viable and fertile. |
References | Acta Med. Okayama, 68(2):63-78 (2014). 24743782 Cancer Res., 68, 8333-8341 (2008). 18922905 Biochem. Biophys. Res. Commun., 268, 20-24 (2000). 10652205 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP |
Ordering Information | |
---|---|
Donor DNA | Phage P1 loxP site, mouse Dkk3 genomic DNA (NCBI.No.BC046304) |
Research application | Cancer Research Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Acta Med. Okayama, 68(2):63-78 (2014). |
Depositor | Hiromi Kumon (Momotaro-Gene Inc.) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |