Strain Data Sheet

RBRC05742

Strain Information

Image
BRC No.RBRC05742
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Gpr141<tm1Rygo>
Former Common nameGPR141 KO, B6-Gpr141 KO
H-2 Haplotype
ES Cell lineE14TG2a [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Dr. Ryo Goitsuka, Tokyo University of Science, Research Institute for Biomedical Sciences in 2010. E14TG2a ES cells were used. The mutant mice were crossed to C57BL/6 over 5 times.
Strain descriptionGpr141 gene knockout mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6NJcl]
References
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.
Fredriksson R, Hoglund P J, Gloriam D E, Lagerstrom M C, Schioth H B
FEBS Lett., 554(3):381-388 (2003). 14623098

J. Leukoc. Biol., qiae009 (2024). doi: 10.1093/jleuko/qiae009. 38226682

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Gpr141G protein-coupled receptor 14113Gpr141targeted mutation 1, Ryo Goitsuka
loxPphage P1 loxP13loxP
loxPphage P1 loxP13loxP
neoneomycin resistance gene (E. coli)13

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
  • Detailed phenotype data

    Ordering Information

    Donor DNAE. coli Neomycin resistance gene, lambda bacteriophage P1 loxP sequence
    Research applicationCre/loxP system
    Sensorineural Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Leukoc. Biol., qiae009 (2024). doi: 10.1093/jleuko/qiae009.
    DepositorRyo Goitsuka (Tokyo University of Science)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data