Strain Information | |
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Image | |
BRC No. | RBRC05742 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Gpr141<tm1Rygo> |
Former Common name | GPR141 KO, B6-Gpr141 KO |
H-2 Haplotype | |
ES Cell line | E14TG2a [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Dr. Ryo Goitsuka, Tokyo University of Science, Research Institute for Biomedical Sciences in 2010. E14TG2a ES cells were used. The mutant mice were crossed to C57BL/6 over 5 times. |
Strain description | Gpr141 gene knockout mice. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6NJcl] |
References | Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. Fredriksson R, Hoglund P J, Gloriam D E, Lagerstrom M C, Schioth H B FEBS Lett., 554(3):381-388 (2003). 14623098J. Leukoc. Biol., qiae009 (2024). doi: 10.1093/jleuko/qiae009. 38226682 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Gpr141 | G protein-coupled receptor 141 | 13 | Gpr141 | targeted mutation 1, Ryo Goitsuka | |||
loxP | phage P1 loxP | 13 | loxP | ||||
loxP | phage P1 loxP | 13 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 13 |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | E. coli Neomycin resistance gene, lambda bacteriophage P1 loxP sequence |
Research application | Cre/loxP system Sensorineural Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Leukoc. Biol., qiae009 (2024). doi: 10.1093/jleuko/qiae009. |
Depositor | Ryo Goitsuka (Tokyo University of Science) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |