Strain Information | |
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Image | |
BRC No. | RBRC05735 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | STOCK Izumo3<tm1Osb> |
Former Common name | Izumo3 KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | Jcl:B6D2F1 |
Appearance | |
Strain development | Developed by Naokazu Inoue, Research Institute for Microbial Diseases, Osaka University in 2012. C57BL/6 and DBA/2 mixed background. |
Strain description | Izumo3 knockout mice. Homozygous mutant males have a tendency to exhibit infertility. |
Colony maintenance | Heterozygote x Wild-type [or Crossing to Jcl : B6D2F1] |
References | Mol. Reprod. Dev., (2021). doi: 10.1002/mrd.23520. 34114279 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Izumo3IZUMO family member 34Izumo3 <tm1Osb>targeted mutation 1, Research Institute for Microbial Diseases, Osaka University Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site4Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP4loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4neo; neomycin;human phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | yeast FRT (flipase recombination target) site, Phage P1 loxP site, human PGK promoter, E. coli Neomycin resistance gene, human PGK poly (A), mouse Izumo3 genomic DNA |
Research application | Developmental Biology Research Immunology and Inflammation Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. Mol. Reprod. Dev., (2021). doi: 10.1002/mrd.23520.RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (https://www.ccb.osaka-u.ac.jp/en/). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
Depositor | Naokazu Inoue (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |