Strain Information | |
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Image | |
BRC No. | RBRC05727 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Syngr4<tm1Osb> |
Former Common name | Syngr4 KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Takao Fujimoto and Masaru Okabe, Research Institute for Microbial Diseases, Osaka University in 2011. |
Strain description | Syngr4 gene knockout mice. Exon 2 of Syngr4 was replaced with a floxed neo cassette. |
Colony maintenance | Heterozygote x Wild-type [or Crossing to C57BL/6NJcl] |
References | Proc. Natl. Acad. Sci. USA, 113(28):7704-10 (2016). 27357688 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Syngr4synaptogyrin 47Syngr4 <tm1Osb>targeted mutation 1, Research Institute for Microbial Diseases, Osaka University Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site7Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse Syngr4 genomic DNA, E. coli Neomycin resistance gene, yeast FRT (flippase recombination target) sites, Phage P1 loxP, mouse phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter, polyadenylation signal (synthetic) |
Research application | Cre/loxP system Developmental Biology Research FLP/frt system |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 113(28):7704-10 (2016). RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (https://www.ccb.osaka-u.ac.jp/en/). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
Depositor | Masaru Okabe (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |